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• Prospective cohort study with gene by diet analysis Date verified

  Low-carbohydrate and low-fat diets, genetic susceptibility, and long-term risk of dementia: a prospective cohort study

  Among 5,301 US adults aged 55 and over followed for about nine years, a low-carbohydrate eating pattern tracked with lower dementia risk and a low-fat one did not. But splitting each pattern by food quality reversed the picture within it: plant based and higher quality versions tracked with less dementia, animal based and lower quality versions with more. Inherited risk did not change the pattern.

  The American Journal of · Chen et al. · Zhejiang University School of Medicine and Harvard T.H. Chan School of Public Health · 7 August 2026 · PMID 42567320

  diet-qualitydietary-patternscarbohydrateepidemiologycognition