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• Critical narrative review Published online 19 August 2026 and assigned to volume 256, pages 91 to 104. The online date is the one used here.

  The case for stacking Nrf2 activating plant compounds on top of exercise in older adults rests on cells and rodents, not people

  A critical review of exercise, redox balance and ageing finds the popular idea of pairing compounds such as astaxanthin, curcumin or sulforaphane with training is not supported by current clinical evidence. Almost all the encouraging work sits in cell culture and rodent models, with very little human data in older populations.

  Free Radical Biology and · Traustadottir et al. · Northern Arizona University · 19 August 2026 · PMID 42617706

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