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• Four arm randomised trial with blinded outcome assessment Date verified

  Comparative Effects of Four Dietary Approaches on Symptom Severity and Quality of Life in Irritable Bowel Syndrome: A Randomized Controlled Trial

  Adults with irritable bowel syndrome were put on one of four eating plans for four weeks. Symptom scores dropped in all four, but fell further on the two low FODMAP plans than on traditional dietary advice, while quality of life improved by a similar amount in every group.

  Digestive Diseases and Sciences · Otay et al. · Gaziantep University · 20 July 2026 · PMID 42474623

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• Open label randomised controlled trial PubMed records 13 January 2026 as the publication date. Volume 32, issue 3, pages 1023 to 1033.

  Five fasting mimicking days a month beat carrying on as normal in Crohn's disease, and the stool marker moved with it

  Ninety seven adults with mild to moderate Crohn's disease. Sixty five did five days a month of a fasting mimicking diet for three months. Seven in ten met the response threshold against four in ten of the control group, and faecal calprotectin fell twenty two percent while it rose in the control arm.

  Nature Medicine 32(3):1023 to · Kulkarni et al. · the Division of Gastroenterology and Hepatology at Stanford University School of Medicine · 13 January 2026 · PMID 41530382

  gut-healthimmunologygeneral-nutritionibs