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• Mouse experiments, alongside a separate observational cohort of people Date verified

  Dietary intervention through bacterial-derived butyrate elicits anti-tumor activity and increases anti-PD-1 response

  In mice, adding the fermentable fibre inulin to the diet slowed tumour growth and made anti-PD-1 immunotherapy work better, and butyrate made by gut bacteria reproduced that effect on its own. In the study's separate group of 117 human lung cancer patients, fibre intake was not linked to survival at all.

  Gut Microbes · Benlaifaoui et al. · Centre de Recherche du CHUM, Montreal · 15 July 2026 · PMID 42454784

  gut-sciencefibermicrobiomeimmunology