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• Four arm randomised trial with blinded outcome assessment Date verified

  Comparative Effects of Four Dietary Approaches on Symptom Severity and Quality of Life in Irritable Bowel Syndrome: A Randomized Controlled Trial

  Adults with irritable bowel syndrome were put on one of four eating plans for four weeks. Symptom scores dropped in all four, but fell further on the two low FODMAP plans than on traditional dietary advice, while quality of life improved by a similar amount in every group.

  Digestive Diseases and Sciences · Otay et al. · Gaziantep University · 20 July 2026 · PMID 42474623

  ibsgut-sciencenutrition
• Mouse experiments, alongside a separate observational cohort of people Date verified

  Dietary intervention through bacterial-derived butyrate elicits anti-tumor activity and increases anti-PD-1 response

  In mice, adding the fermentable fibre inulin to the diet slowed tumour growth and made anti-PD-1 immunotherapy work better, and butyrate made by gut bacteria reproduced that effect on its own. In the study's separate group of 117 human lung cancer patients, fibre intake was not linked to survival at all.

  Gut Microbes · Benlaifaoui et al. · Centre de Recherche du CHUM, Montreal · 15 July 2026 · PMID 42454784

  gut-sciencefibermicrobiomeimmunology