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• Randomised double blind placebo controlled trial Date verified

  Effects of creatine supplementation with and without exercise and diet intervention on body composition, cognitive function, and markers of health in middle-aged and older adults

  Sixty four adults aged 45 to 65 took creatine or a matched placebo for twelve weeks, some alongside an exercise and weight loss programme and some without. Creatine increased lean tissue mass and strength in both settings. The cognitive and blood marker results, which are the ones currently driving the supplement's marketing, are labelled exploratory by the authors themselves.

  Journal of the International · Chun et al. · Texas A and M University · 11 August 2026 · PMID 42578920

  supplementsproteinrecoverymetabolism
• Agency case report, not peer reviewed 3 Aug 2026 is the date of the NutraIngredients report; the ANSES report's own publication date was not separately stated in the digest.

  One extreme supplement overuse case ended in liver failure and a transplant

  France's food safety agency ANSES reported liver decompensation, kidney failure and transplant in a 54 year old with pre existing liver disease who massively over consumed mass gainer and whey, rating the supplement link very likely for the liver injury.

  3 August 2026

  supplementsproteinfood-policy
• Randomized crossover, multi site Published 20 Feb 2026. Press release 4 Aug 2026. Cite the February date.

  Four weeks plant based, and recreational athletes performed about the same

  In a four site randomized crossover using university dining halls, 36 recreational athletes showed no significant difference in a 12 minute run or composite machine strength between a plant based and an omnivorous month, though the strength interval leaned toward the omnivore diet.

  Nutrition Journal · Raygoza et al. · 20 February 2026

  proteinfibergeneral-nutritionresearch-methods
• Randomised controlled trial with supervised training PubMed records 16 April 2025 as the publication date. Volume 22, issue 1, article 2492184.

  With calories and protein matched, the lifters on a sixteen eight window did less total work and their squat went up less

  Seventeen well trained lifters, eight weeks of supervised training, both arms ten percent above maintenance at 2.2 grams of protein per kilogram, and intake statistically matched. The fasting arm did fewer repetitions, rated its daily energy lower, and gained about four kilograms less on the squat.

  Journal of the International · Blake et al. · the Center for Sport Performance at California State University Fullerton · 16 April 2025 · PMID 40241374

  strengthproteinmetabolismendurance-fueling
• Four arm randomised controlled trial PubMed records 19 March 2025 as the publication date. Volume 22, issue 1, article 2481127.

  A ten hour eating window on its own removed two and a third kilograms of lean tissue and no fat at all

  Four arms for eight weeks: a ten hour eating window, resistance training, both, and neither. The window alone dropped more than two kilograms of body weight, and the fat mass did not move. What came off was lean tissue. Adding the training changed the answer completely.

  Journal of the International · Cui et al. · the Institute of Human Movement and Sports Engineering at Zhejiang Normal University · 19 March 2025 · PMID 40108888

  strengthmetabolismproteingeneral-nutrition