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• Double blind counterbalanced crossover First published online 20 August 2026. Still online ahead of print, so no volume, issue or page range exists yet.

  A capsaicin capsule before lifting left leg press repetitions and jump height unchanged, and expectancy did not move them either

  Sixteen advanced resistance trained men lifted and jumped under capsaicin, placebo and no supplement at all. All three conditions came out the same. The third arm was there to catch a belief effect, and it did not find one.

  Nutrition and Health · de et al. · Paulista University · 20 August 2026 · PMID 42623016

  supplementsresearch-methodsrecoveryendurance-fuelingstrength
• Randomised double blind placebo controlled trial Date verified

  Effects of creatine supplementation with and without exercise and diet intervention on body composition, cognitive function, and markers of health in middle-aged and older adults

  Sixty four adults aged 45 to 65 took creatine or a matched placebo for twelve weeks, some alongside an exercise and weight loss programme and some without. Creatine increased lean tissue mass and strength in both settings. The cognitive and blood marker results, which are the ones currently driving the supplement's marketing, are labelled exploratory by the authors themselves.

  Journal of the International · Chun et al. · Texas A and M University · 11 August 2026 · PMID 42578920

  supplementsproteinrecoverymetabolism
• Single arm interventional heat acclimation study Date verified

  Relationships between plasma volume, fluid regulatory hormones, and maximal oxygen uptake following fixed-workload heat acclimation in men and women

  Twenty six men and women did ten days of fixed workload exercise in a hot chamber. They adapted in all the usual ways, running cooler with lower heart rates and more sweat. But blood plasma volume held steady and maximal oxygen uptake did not move, which are the two changes heat training is often expected to deliver.

  American Journal of Physiology, · Greenfield et al. · US Army Research Institute of Environmental Medicine · 7 August 2026 · PMID 42566767

  heathydrationendurance-fuelingrecovery
• Cross sectional observational study with muscle biopsies Date verified

  Aging is associated with altered estrogen receptor expression and alters redox protein balance in human female skeletal muscle

  Muscle biopsies from 107 women aged 19 to 70 show that the main estrogen receptor in skeletal muscle is about half as abundant in the oldest group as in the youngest, and that receptor levels track proteins governing nitric oxide and oxidative balance. Everything measured here is protein abundance. No oxidative stress outcome and no muscle function outcome was measured at all.

  GeroScience · Tamariz-Ellemann et al. · University of Copenhagen · 7 August 2026 · PMID 42566157

  oxidative-stressfemale-athletesrecoverymetabolism
• Randomised crossover plus parallel group trial Date verified

  Three months of ice baths left the redox and mitochondrial adaptations intact

  Trained men lifted twice a week for three months, half of them sitting in cold water after every session. Redox gene expression and mitochondrial enzyme activity rose the same amount in both groups.

  Experimental Physiology, online ahead · Roberts et al. · The University of Queensland · 22 July 2026 · PMID 42487262

  oxidative-stressrecoverymitochondria